Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 8/20 | 0.32 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | CHKB | Q9Y259 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046755 | 0.89 | PDE10A (0.32) | SPR | |
| SCHEMBL25048625 | 0.86 | — | — | |
| SCHEMBL25047585 | 0.84 | NT5E (0.36) | CHKA | |
| SCHEMBL25048135 | 0.82 | — | — | |
| SCHEMBL25048345 | 0.81 | CHKA (0.35) | CHKACHKB | |
| SCHEMBL25048059 | 0.81 | CHKA (0.32) | CHKAPIK3CACHKB | |
| SCHEMBL25046781 | 0.81 | CHKA (0.38) | CHKACHKB | |
| SCHEMBL25048731 | 0.80 | PIK3CA (0.36) | CHKAPIK3CACHKB | |
| SCHEMBL25047724 | 0.78 | CHKA (0.37) | CHKACHKB | |
| SCHEMBL25048836 | 0.77 | PRMT5 (0.39) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |