Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 4/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049211 | 0.89 | NPBWR1 (0.35) | NPBWR1MCHR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL25048731 | 0.86 | PIK3CA (0.36) | CHKACHKB | |
| SCHEMBL25048345 | 0.86 | CHKA (0.35) | CHKACHKB | |
| SCHEMBL25047724 | 0.84 | CHKA (0.37) | CHKACHKB | |
| SCHEMBL25048480 | 0.81 | CHKA (0.34) | CHKACHKB | |
| SCHEMBL25048059 | 0.81 | CHKA (0.32) | CHKACHKB | |
| SCHEMBL25047669 | 0.81 | CHKA (0.33) | CHKACHKB | |
| SCHEMBL25048803 | 0.80 | PIP4K2A (0.35) | CHKACHKBADRA1A | |
| SCHEMBL25046693 | 0.79 | CHKA (0.33) | CHKA | |
| SCHEMBL31617909 | 0.77 | CHKA (0.35) | CHKACHKBMCHR1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |