Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 6/20 | 0.37 |
| ▸ | CHKB | Q9Y259 | 4/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048731 | 0.86 | PIK3CA (0.36) | CHKACHKBPIP4K2A | |
| SCHEMBL25046781 | 0.84 | CHKA (0.38) | CHKACHKB | |
| SCHEMBL25046822 | 0.79 | METTL3 (0.39) | — | |
| SCHEMBL25047723 | 0.79 | ACACB (0.31) | — | |
| SCHEMBL25048345 | 0.78 | CHKA (0.35) | CHKACHKB | |
| SCHEMBL25047669 | 0.78 | CHKA (0.33) | CHKACHKB | |
| SCHEMBL25048059 | 0.78 | CHKA (0.32) | CHKACHKB | |
| SCHEMBL25049274 | 0.77 | CHKA (0.35) | CHKACHKBPDE8A | |
| SCHEMBL25048458 | 0.77 | CHKA (0.34) | CHKACHKB | |
| SCHEMBL25048806 | 0.76 | CHKA (0.35) | CHKACHKBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |