Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 7/20 | 0.31 |
| ▸ | CHKB | Q9Y259 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046856 | 0.92 | WNT1 (0.31) | WNT1GSK3BDYRK1A | |
| SCHEMBL25049304 | 0.85 | CHKA (0.30) | CHKA | |
| SCHEMBL25048480 | 0.83 | CHKA (0.34) | CHKACHKB | |
| SCHEMBL25049069 | 0.83 | CHKA (0.33) | CHKACHKB | |
| SCHEMBL25047719 | 0.80 | — | — | |
| SCHEMBL25047766 | 0.78 | — | — | |
| SCHEMBL25048176 | 0.74 | KDR (0.31) | — | |
| SCHEMBL30940807 | 0.73 | DYRK1A (0.32) | WNT1GSK3BDYRK1A | |
| SCHEMBL25048465 | 0.72 | NT5E (0.31) | — | |
| SCHEMBL25048345 | 0.71 | CHKA (0.35) | CHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |