Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CHKB | Q9Y259 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048176 | 0.91 | KDR (0.31) | KDR | |
| SCHEMBL25049304 | 0.90 | CHKA (0.30) | CHKA | |
| SCHEMBL25046757 | 0.87 | PRMT5 (0.38) | — | |
| SCHEMBL25048480 | 0.86 | CHKA (0.34) | CHKACHKB | |
| SCHEMBL25049159 | 0.83 | PIP4K2A (0.34) | KDR | |
| SCHEMBL25047722 | 0.83 | WNT1 (0.31) | CHKACHKB | |
| SCHEMBL25049274 | 0.81 | CHKA (0.35) | CHKACHKB | |
| SCHEMBL25049064 | 0.80 | PRMT5 (0.41) | — | |
| SCHEMBL25047766 | 0.80 | — | — | |
| SCHEMBL25046778 | 0.78 | CHKA (0.37) | CHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |