Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047772 | 0.78 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL25048272 | 0.77 | PRMT5 (0.40) | PRMT5WDR77ADK | |
| SCHEMBL25047453 | 0.75 | PRMT5 (0.40) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL21312931 | 0.70 | PRMT5 (0.40) | PRMT5WDR77METTL3 | |
| SCHEMBL21312978 | 0.69 | PRMT5 (0.41) | PRMT5WDR77METTL3 | |
| SCHEMBL24067669 | 0.69 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL24090715 | 0.68 | PRMT5 (0.43) | PRMT5WDR77ADK | |
| SCHEMBL25049137 | 0.67 | NNMT (0.36) | PRMT5WDR77 | |
| SCHEMBL24067682 | 0.67 | PRMT5 (0.42) | PRMT5WDR77METTL3 | |
| SCHEMBL22002179 | 0.67 | PRMT5 (0.42) | PRMT5WDR77ADKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |