Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047775 | 0.79 | PIP4K2A (0.35) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25047729 | 0.78 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL24067669 | 0.78 | PRMT5 (0.34) | PRMT5WDR77PIP4K2A | |
| SCHEMBL25049137 | 0.77 | NNMT (0.36) | PRMT5WDR77PIP4K2A | |
| SCHEMBL19344195 | 0.72 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL20049423 | 0.72 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL16769947 | 0.69 | PRMT5 (0.44) | PRMT5WDR77PIP4K2A | |
| SCHEMBL22002062 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL25048850 | 0.69 | NNMT (0.36) | — | |
| SCHEMBL21129817 | 0.69 | PRMT5 (0.33) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |