Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CHKA | P35790 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941554 | 1.00 | METTL3 (0.35) | METTL3MAPK1CHKAGAACHKB | |
| SCHEMBL30941728 | 1.00 | METTL3 (0.35) | METTL3MAPK1CHKAGAACHKB | |
| SCHEMBL30940742 | 0.92 | HTR2A (0.32) | METTL3MAPK1GAAHTR2AHTR2C | |
| SCHEMBL25048303 | 0.92 | HTR2A (0.32) | METTL3MAPK1GAAHTR2AHTR2C | |
| SCHEMBL25048847 | 0.92 | METTL3 (0.34) | METTL3 | |
| SCHEMBL25048457 | 0.86 | METTL3 (0.42) | METTL3BACE1 | |
| SCHEMBL30940938 | 0.86 | METTL3 (0.42) | METTL3BACE1 | |
| SCHEMBL25049313 | 0.86 | METTL3 (0.36) | METTL3 | |
| SCHEMBL30940973 | 0.86 | METTL3 (0.36) | METTL3 | |
| SCHEMBL25047761 | 0.85 | PRMT5 (0.39) | METTL3MAPK1CHKAGAACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |