Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 18/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941259 | 1.00 | METTL3 (0.51) | METTL3CA2PRMT5DOT1L | |
| SCHEMBL25047779 | 0.91 | METTL3 (0.50) | METTL3CA2DOT1L | |
| SCHEMBL30941571 | 0.91 | METTL3 (0.50) | METTL3CA2DOT1L | |
| SCHEMBL31618086 | 0.90 | METTL3 (0.59) | METTL3CA2PRMT5DOT1L | |
| SCHEMBL25047810 | 0.90 | METTL3 (0.59) | METTL3CA2PRMT5DOT1L | |
| SCHEMBL25046820 | 0.90 | CA2 (0.47) | METTL3CA2PRMT5 | |
| SCHEMBL31618068 | 0.90 | CA2 (0.47) | METTL3CA2PRMT5 | |
| SCHEMBL25046614 | 0.88 | METTL3 (0.59) | METTL3CA2PRMT5 | |
| SCHEMBL31618042 | 0.88 | METTL3 (0.59) | METTL3CA2PRMT5 | |
| SCHEMBL25047860 | 0.86 | METTL3 (0.60) | METTL3CA2PRMT5DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |