Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 14/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618039 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3FFAR1 | |
| SCHEMBL31618056 | 0.94 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL25048701 | 0.91 | PRMT5 (0.40) | PRMT5FFAR1 | |
| SCHEMBL31618015 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL25048777 | 0.85 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL25048258 | 0.84 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL31618087 | 0.84 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL25049348 | 0.83 | IGF1R (0.37) | PRMT5WDR77 | |
| SCHEMBL31617999 | 0.83 | PRMT5 (0.40) | PRMT5WDR77 | |
| SCHEMBL25049352 | 0.83 | PRMT5 (0.42) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |