Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049339 | 0.83 | PRMT5 (0.41) | PRMT5WDR77NT5EADORA3ADORA2A | |
| SCHEMBL25048345 | 0.82 | CHKA (0.35) | NT5EADORA3ADORA2AADORA1 | |
| SCHEMBL25048290 | 0.77 | PLG (0.37) | PRMT5WDR77NT5E | |
| SCHEMBL31618004 | 0.71 | METTL3 (0.43) | PRMT5WDR77NT5E | |
| SCHEMBL25048467 | 0.71 | PRMT5 (0.39) | PRMT5WDR77NT5E | |
| SCHEMBL25048785 | 0.71 | METTL3 (0.43) | PRMT5WDR77NT5E | |
| SCHEMBL25046819 | 0.70 | PRMT5 (0.40) | PRMT5WDR77NT5E | |
| SCHEMBL30941211 | 0.70 | PRMT5 (0.40) | PRMT5WDR77NT5E | |
| SCHEMBL25048572 | 0.69 | PRMT5 (0.39) | PRMT5WDR77NT5E | |
| SCHEMBL25048836 | 0.69 | PRMT5 (0.39) | PRMT5WDR77NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |