Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 2/20 | 0.34 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | TARS1 | P26639 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046776 | 0.78 | NT5E (0.39) | NT5EPRMT5WDR77METTL3 | |
| SCHEMBL25048343 | 0.77 | PRMT5 (0.36) | NT5EPRMT5WDR77 | |
| SCHEMBL25049345 | 0.76 | CHKA (0.41) | BACE1CHKANT5ECHKBPRMT5 | |
| SCHEMBL25046778 | 0.75 | CHKA (0.37) | CHKANT5ECHKB | |
| SCHEMBL25048808 | 0.72 | NT5E (0.39) | NT5EPRMT5WDR77METTL3 | |
| SCHEMBL25048466 | 0.71 | PRMT5 (0.39) | CHKANT5ECHKBPRMT5WDR77 | |
| SCHEMBL30941587 | 0.71 | PRMT5 (0.39) | CHKANT5ECHKBPRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL30940867 | 0.70 | PRMT5 (0.38) | CHKANT5ECHKBPRMT5WDR77 | |
| SCHEMBL25048806 | 0.70 | CHKA (0.35) | CHKANT5ECHKBDHFR | |
| SCHEMBL31617909 | 0.70 | CHKA (0.35) | CHKANT5ECHKBDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |