Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 8/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047425 | 0.87 | PIP4K2A (0.39) | PIP4K2APRMT5WDR77NNMTDRD2 | |
| SCHEMBL25048961 | 0.83 | DRD2 (0.40) | PIP4K2APRMT5WDR77NNMTDRD2 | |
| SCHEMBL25049159 | 0.82 | PIP4K2A (0.34) | PIP4K2APRMT5WDR77NNMT | |
| SCHEMBL25048722 | 0.78 | PIP4K2A (0.39) | PIP4K2APRMT5WDR77NNMTSLC22A12 | |
| SCHEMBL25047597 | 0.78 | PIP4K2A (0.37) | PIP4K2APRMT5WDR77NNMT | |
| SCHEMBL16967987 | 0.77 | PIP4K2A (0.49) | PIP4K2APRMT5WDR77SLC22A12 | |
| SCHEMBL25046606 | 0.74 | RIPK2 (0.44) | PRMT5WDR77 | |
| SCHEMBL25049134 | 0.74 | PIP4K2A (0.46) | PIP4K2APRMT5WDR77NNMTSLC22A12 | |
| SCHEMBL18571707 | 0.74 | ABL1 (0.44) | PIP4K2APRMT5WDR77NNMTSLC22A12 | |
| SCHEMBL25048378 | 0.72 | PRMT5 (0.45) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |