Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047464 | 0.83 | PRMT5 (0.53) | PRMT5WDR77METTL3 | |
| SCHEMBL25047463 | 0.81 | PRMT5 (0.40) | PRMT5WDR77ADK | |
| SCHEMBL29510138 | 0.72 | AHCY (0.61) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL25048272 | 0.71 | PRMT5 (0.40) | PRMT5WDR77ADK | |
| SCHEMBL18922654 | 0.70 | PRMT5 (0.48) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL25048296 | 0.70 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL15829524 | 0.70 | AHCY (0.63) | PRMT5WDR77METTL3 | |
| SCHEMBL31618075 | 0.69 | AHCY (0.68) | PRMT5WDR77METTL3 | |
| SCHEMBL25048371 | 0.69 | AHCY (0.68) | PRMT5WDR77METTL3 | |
| SCHEMBL24465141 | 0.68 | PRMT5 (0.67) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |