Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048378 | 0.81 | PRMT5 (0.45) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25048545 | 0.81 | PRMT5 (0.46) | PRMT5WDR77ADK | |
| SCHEMBL25047434 | 0.80 | PRMT5 (0.43) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25047449 | 0.77 | RIPK2 (0.42) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25047464 | 0.76 | PRMT5 (0.53) | PRMT5WDR77 | |
| SCHEMBL25046606 | 0.76 | RIPK2 (0.44) | PRMT5MEN1WDR77 | |
| SCHEMBL14447403 | 0.75 | MEN1 (0.43) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25046760 | 0.74 | PRMT5 (0.40) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25049275 | 0.74 | PRMT5 (0.45) | PRMT5MEN1WDR77ADK | |
| SCHEMBL25047848 | 0.73 | ADK (0.50) | PRMT5MEN1WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |