Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBA6 | A0AVT1 | 5/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.41 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | NEDD8 | Q15843 | 1/20 | 0.41 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186224 | 1.00 | UBA6 (0.42) | UBA6PRMT5WDR77NAE1CA2 | |
| SCHEMBL13170707 | 0.88 | UBA6 (0.42) | UBA6PRMT5WDR77 | |
| SCHEMBL1947419 | 0.85 | UBA6 (0.41) | UBA6PRMT5WDR77NAE1CA2 | |
| SCHEMBL19563037 | 0.85 | ADK (0.48) | PRMT5WDR77 | |
| SCHEMBL18589317 | 0.85 | UBA6 (0.41) | UBA6PRMT5WDR77NAE1CA2 | |
| SCHEMBL936138 | 0.85 | UBA6 (0.41) | UBA6PRMT5WDR77NAE1CA2 | |
| SCHEMBL191943 | 0.85 | ADK (0.48) | PRMT5WDR77 | |
| SCHEMBL17866020 | 0.82 | UBA6 (0.43) | UBA6PRMT5WDR77 | |
| SCHEMBL192779 | 0.81 | NAE1 (0.61) | UBA6NAE1CA2GRK5CSNK1A1 | |
| SCHEMBL17875179 | 0.81 | NAE1 (0.61) | UBA6NAE1CA2GRK5CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |