Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RBBP5 | Q15291 | 2/20 | 0.34 |
| ▸ | DPY30 | Q9C005 | 2/20 | 0.34 |
| ▸ | ASH2L | Q9UBL3 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.33 |
| ▸ | AMD1 | P17707 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047819 | 0.76 | WDR5 (0.33) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL25047839 | 0.75 | DOT1L (0.34) | PI4KAPI4K2BPI4K2API4KBWDR5 | |
| SCHEMBL25047774 | 0.75 | DOT1L (0.38) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14703565 | 0.73 | DOT1L (0.49) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL804138 | 0.73 | DOT1L (0.49) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL17777367 | 0.71 | DOT1L (0.61) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9970622 | 0.70 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL15395441 | 0.70 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL15395684 | 0.70 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL19532451 | 0.69 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |