Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RBBP5 | Q15291 | 2/20 | 0.33 |
| ▸ | DPY30 | Q9C005 | 2/20 | 0.33 |
| ▸ | ASH2L | Q9UBL3 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.33 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047819 | 0.89 | WDR5 (0.33) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL23120522 | 0.81 | CPB2 (0.31) | PRMT5WDR77 | |
| SCHEMBL25046560 | 0.80 | ADK (0.41) | DOT1LPRMT5WDR77PI4KAPI4K2B | |
| SCHEMBL23120354 | 0.80 | NAPEPLD (0.32) | PRMT5WDR77 | |
| SCHEMBL25048314 | 0.78 | CPB2 (0.32) | PRMT5WDR77 | |
| SCHEMBL25047411 | 0.77 | HDAC3 (0.31) | PRMT5WDR77 | |
| SCHEMBL25048673 | 0.75 | PI4KA (0.38) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL23120248 | 0.74 | NPEPPS (0.32) | — | |
| SCHEMBL18571700 | 0.74 | PI4KA (0.47) | PRMT5WDR77PI4KAPI4K2BPI4K2A | |
| SCHEMBL25949203 | 0.74 | PI4KA (0.47) | PRMT5WDR77PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |