Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778529 | 0.66 | HDAC4 (0.63) | KMOHDAC8HDAC4HDAC2DRD3 | |
| SCHEMBL16957282 | 0.66 | KMO (0.64) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL24934144 | 0.65 | MASP2 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL24934027 | 0.65 | CYP3A4 (0.37) | ALDH1A1POLB | |
| SCHEMBL6051833 | 0.65 | KMO (0.96) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| Hydrogen Peroxide SCHEMBL11391460 | 0.65 | KMO (0.71) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL16961239 | 0.64 | KMO (0.57) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL16957389 | 0.64 | KMO (0.57) | KMOHDAC8HDAC4HDAC2SERPINE1 | |
| SCHEMBL669730 | 0.64 | KMO (0.64) | KMOHDAC8HDAC4HDAC2DRD3 | |
| SCHEMBL5667650 | 0.64 | KMO (0.64) | KMOHDAC8HDAC4HDAC2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |