Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 5/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 11/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.36 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046776 | 0.89 | NT5E (0.39) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25049345 | 0.88 | CHKA (0.41) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL31618004 | 0.82 | METTL3 (0.43) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25048785 | 0.82 | METTL3 (0.43) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25048835 | 0.81 | PRMT5 (0.41) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL30941587 | 0.81 | PRMT5 (0.39) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25048466 | 0.81 | PRMT5 (0.39) | NT5EPRMT5WDR77METTL3METTL14 | |
| Hydrochloric Acid SCHEMBL30940867 | 0.81 | PRMT5 (0.38) | NT5EPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25048806 | 0.80 | CHKA (0.35) | NT5E | |
| SCHEMBL31617909 | 0.80 | CHKA (0.35) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |