Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 8/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048466 | 0.91 | PRMT5 (0.39) | CHKACHKBPRMT5WDR77AHCY | |
| SCHEMBL30941587 | 0.91 | PRMT5 (0.39) | CHKACHKBPRMT5WDR77AHCY | |
| Hydrochloric Acid SCHEMBL30940867 | 0.90 | PRMT5 (0.38) | CHKACHKBPRMT5WDR77AHCY | |
| SCHEMBL25048467 | 0.88 | PRMT5 (0.39) | PRMT5WDR77AHCYMETTL3METTL14 | |
| SCHEMBL25048808 | 0.88 | NT5E (0.39) | PRMT5WDR77AHCYMETTL3METTL14 | |
| SCHEMBL25046776 | 0.88 | NT5E (0.39) | PRMT5WDR77AHCYMETTL3METTL14 | |
| SCHEMBL25049347 | 0.87 | PRMT5 (0.38) | PRMT5WDR77METTL3METTL14NT5E | |
| SCHEMBL25047896 | 0.85 | NT5E (0.37) | CHKAPRMT5WDR77METTL3METTL14 | |
| SCHEMBL30941009 | 0.85 | NT5E (0.37) | CHKAPRMT5WDR77METTL3METTL14 | |
| SCHEMBL25046822 | 0.85 | METTL3 (0.39) | PRMT5WDR77AHCYMETTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |