Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 16/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KIF5B | P33176 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940806 | 1.00 | METTL3 (0.47) | METTL3CA2PRMT5RETKIF5B | |
| SCHEMBL25048887 | 0.91 | METTL3 (0.49) | METTL3CA2PRMT5WDR77 | |
| SCHEMBL30941129 | 0.91 | METTL3 (0.49) | METTL3CA2PRMT5WDR77 | |
| SCHEMBL30940999 | 0.91 | METTL3 (0.52) | METTL3CA2PRMT5 | |
| SCHEMBL25046807 | 0.91 | METTL3 (0.52) | METTL3CA2PRMT5 | |
| SCHEMBL25048000 | 0.89 | METTL3 (0.44) | METTL3PRMT5RETKIF5B | |
| SCHEMBL30941705 | 0.88 | METTL3 (0.57) | METTL3CA2PRMT5 | |
| SCHEMBL25048886 | 0.88 | METTL3 (0.57) | METTL3CA2PRMT5 | |
| SCHEMBL25048002 | 0.86 | RET (0.42) | RETKIF5B | |
| SCHEMBL25048822 | 0.84 | METTL3 (0.49) | METTL3CA2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |