Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 4/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | ABL2 | P42684 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941365 | 1.00 | CNR1 (0.35) | CNR1TNK2BTKSRCEGFR | |
| SCHEMBL25048816 | 0.86 | TNK2 (0.33) | TNK2GRM5 | |
| SCHEMBL30940953 | 0.86 | TNK2 (0.33) | TNK2GRM5 | |
| SCHEMBL30941397 | 0.85 | GPR119 (0.37) | SRCEGFRGPR119ABL1ABL2 | |
| SCHEMBL25048941 | 0.83 | SRC (0.38) | CNR1TNK2BTKSRCEGFR | |
| SCHEMBL25048595 | 0.80 | GRM5 (0.32) | GRM5 | |
| SCHEMBL30940882 | 0.80 | GRM5 (0.32) | GRM5 | |
| SCHEMBL30941177 | 0.80 | ADK (0.33) | — | |
| SCHEMBL25048597 | 0.76 | ADK (0.35) | FGFR1FGFR4 | |
| SCHEMBL31617954 | 0.76 | ADK (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |