Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ABL2 | P42684 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048478 | 0.89 | METTL3 (0.35) | CA2METTL3PRMT5ABL1EGFR | |
| SCHEMBL30940989 | 0.89 | METTL3 (0.35) | CA2METTL3PRMT5ABL1EGFR | |
| SCHEMBL25047879 | 0.89 | ABL1 (0.39) | ABL1EGFRABL2SRCLMNA | |
| SCHEMBL25048295 | 0.88 | PRMT5 (0.33) | CA2METTL3PRMT5SLC6A2SLC6A4 | |
| SCHEMBL30941294 | 0.88 | METTL3 (0.34) | CA2METTL3PRMT5ABL1EGFR | |
| SCHEMBL31618011 | 0.88 | ABL1 (0.49) | CA2METTL3ABL1EGFRABL2 | |
| SCHEMBL25048714 | 0.88 | ABL1 (0.49) | CA2METTL3ABL1EGFRABL2 | |
| SCHEMBL25049351 | 0.88 | METTL3 (0.45) | CA2METTL3PRMT5 | |
| SCHEMBL25046695 | 0.88 | METTL3 (0.45) | CA2METTL3PRMT5 | |
| SCHEMBL30941447 | 0.88 | METTL3 (0.45) | CA2METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |