Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | ABL2 | P42684 | 5/20 | 0.39 |
| ▸ | SRC | P12931 | 13/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048971 | 0.89 | CA2 (0.38) | ABL1EGFRABL2SRCLMNA | |
| SCHEMBL25047886 | 0.88 | ABL1 (0.35) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL25049370 | 0.87 | SRC (0.35) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL30940989 | 0.79 | METTL3 (0.35) | ABL1EGFRABL2SRC | |
| SCHEMBL25048478 | 0.79 | METTL3 (0.35) | ABL1EGFRABL2SRC | |
| SCHEMBL30941294 | 0.78 | METTL3 (0.34) | ABL1EGFRABL2SRC | |
| SCHEMBL25048295 | 0.78 | PRMT5 (0.33) | — | |
| SCHEMBL30941243 | 0.77 | DOT1L (0.37) | ABL1EGFRABL2SRC | |
| SCHEMBL25048714 | 0.76 | ABL1 (0.49) | ABL1EGFRABL2SRCLCK | |
| SCHEMBL31618011 | 0.76 | ABL1 (0.49) | ABL1EGFRABL2SRCLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |