Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 15/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | ADK | P55263 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049362 | 0.94 | ADK (0.39) | METTL3PRMT5ADKCA2SRC | |
| SCHEMBL30941413 | 0.94 | ADK (0.39) | METTL3PRMT5ADKCA2SRC | |
| SCHEMBL25049087 | 0.87 | RIPK2 (0.36) | ADKSRC | |
| SCHEMBL25048896 | 0.85 | — | — | |
| SCHEMBL30941031 | 0.85 | — | — | |
| SCHEMBL30941403 | 0.78 | ADK (0.46) | METTL3PRMT5ADKCA2 | |
| SCHEMBL25047836 | 0.78 | ADK (0.46) | METTL3PRMT5ADKCA2 | |
| SCHEMBL30940961 | 0.77 | ADK (0.47) | METTL3PRMT5ADKCA2SRC | |
| SCHEMBL25049332 | 0.77 | ADK (0.47) | METTL3PRMT5ADKCA2SRC | |
| SCHEMBL31617956 | 0.76 | ADK (0.32) | METTL3PRMT5ADKWDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |