Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 10/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940961 | 1.00 | ADK (0.47) | ADKCA2METTL3ABL1EGFR | |
| SCHEMBL25047836 | 0.93 | ADK (0.46) | ADKCA2METTL3PRMT5 | |
| SCHEMBL30941403 | 0.93 | ADK (0.46) | ADKCA2METTL3PRMT5 | |
| SCHEMBL30941278 | 0.89 | CA2 (0.45) | CA2METTL3ABL1EGFRABL2 | |
| SCHEMBL25047827 | 0.89 | CA2 (0.45) | CA2METTL3ABL1EGFRABL2 | |
| SCHEMBL25048825 | 0.88 | CA2 (0.52) | ADKCA2METTL3ABL1EGFR | |
| SCHEMBL30941348 | 0.88 | CA2 (0.52) | ADKCA2METTL3ABL1EGFR | |
| SCHEMBL25048519 | 0.88 | CA2 (0.44) | CA2METTL3PRMT5WDR77SRC | |
| SCHEMBL30941450 | 0.88 | CA2 (0.44) | CA2METTL3PRMT5WDR77SRC | |
| SCHEMBL25046809 | 0.87 | CA2 (0.49) | ADKCA2METTL3ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |