Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18968285 | 1.00 | USP2 (0.33) | USP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL23865694 | 0.93 | CHRNA1 (0.37) | USP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10062591 | 0.93 | CHRNA1 (0.37) | USP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL10062590 | 0.91 | CDC42BPB (0.34) | USP2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL12926362 | 0.86 | SIGMAR1 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA1 | |
| SCHEMBL12958765 | 0.86 | SIGMAR1 (0.33) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA1 | |
| SCHEMBL12309899 | 0.86 | — | — | |
| SCHEMBL90414 | 0.84 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA1 | |
| SCHEMBL13859631 | 0.84 | SIGMAR1 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA1 | |
| SCHEMBL26441355 | 0.84 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018810-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |