Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25051605 | 0.81 | EIF2AK4 (0.31) | EIF2AK4 | |
| SCHEMBL25049525 | 0.78 | USP2 (0.34) | EIF2AK4 | |
| SCHEMBL26374604 | 0.78 | USP2 (0.34) | EIF2AK4 | |
| SCHEMBL23107539 | 0.73 | OTUD7B (0.46) | — | |
| Hydrochloric Acid SCHEMBL6641338 | 0.71 | OTUD7B (0.52) | — | |
| SCHEMBL16562302 | 0.71 | OTUD7B (0.39) | — | |
| SCHEMBL29333455 | 0.69 | PDCD1LG2 (0.39) | — | |
| SCHEMBL10263099 | 0.69 | OTUD7B (0.45) | — | |
| SCHEMBL22932089 | 0.69 | CRBN (0.51) | — | |
| Hydrochloric Acid SCHEMBL7548202 | 0.69 | CRBN (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018810-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |