Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049525 | 1.00 | USP2 (0.34) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL16562302 | 0.89 | OTUD7B (0.39) | OTUD7BCRBNNEK2 | |
| SCHEMBL16750994 | 0.84 | OTUD7B (0.42) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL24859554 | 0.84 | OTUD7B (0.50) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL14377176 | 0.84 | OTUD7B (0.50) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL16562318 | 0.80 | — | — | |
| SCHEMBL25049545 | 0.78 | EIF2AK4 (0.30) | EIF2AK4 | |
| SCHEMBL10062592 | 0.76 | CHRM2 (0.42) | OTUD7BNEK2 | |
| SCHEMBL12065328 | 0.75 | GRIN1 (0.36) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL25051605 | 0.74 | EIF2AK4 (0.31) | OTUD7BEIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173016-A1 | KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |