Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23498289 | 0.87 | MEN1 (0.36) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL29812974 | 0.87 | MEN1 (0.36) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL24917988 | 0.86 | MEN1 (0.35) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL25049486 | 0.83 | CYP17A1 (0.33) | CYP17A1PSMB8POLBLMNA | |
| SCHEMBL30781872 | 0.80 | TRPA1 (0.35) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL27100884 | 0.80 | TRPA1 (0.35) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL31670679 | 0.80 | MEN1 (0.36) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL30537698 | 0.80 | MEN1 (0.32) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL24757043 | 0.80 | AAK1 (0.33) | MEN1KMT2ATRPA1EGLN2CYP1A2 | |
| SCHEMBL25405428 | 0.80 | MEN1 (0.32) | MEN1KMT2ATRPA1EGLN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215801-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023098832-A1 | PYRIDOPYRIMIDINE DERIVATIVES SERVING AS SMALL GTP ENZYME KRAS MUTATION INHIBITORS | 思路迪生物医药(上海)有限公司 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023018699-A1 | SELECTIVE KRAS INHIBITORS | ERASCA, INC. (US) | 2023-02-16 | — | — | WO | disclosed |