Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369164 | 0.82 | RNPEP (0.43) | ALDH1A1RNPEPSLC7A5PGRADRA2A | |
| SCHEMBL23205735 | 0.82 | RNPEP (0.43) | ALDH1A1RNPEPSLC7A5PGRADRA2A | |
| SCHEMBL3965956 | 0.82 | RNPEP (0.43) | ALDH1A1RNPEPSLC7A5PGRADRA2A | |
| SCHEMBL18796582 | 0.80 | SLC7A5 (0.37) | RNPEPSLC7A5PGRADRA2AADRA2B | |
| SCHEMBL10076902 | 0.78 | FDPS (0.37) | ALDH1A1TDP1PGRADRA2AADRA2B | |
| SCHEMBL890205 | 0.78 | FDPS (0.37) | ALDH1A1TDP1PGRADRA2AADRA2B | |
| SCHEMBL15044801 | 0.77 | EPHX1 (0.39) | — | |
| SCHEMBL16329864 | 0.76 | ALDH1A1 (0.36) | KISS1RALDH1A1RNPEPTDP1SLC7A5 | |
| SCHEMBL9222665 | 0.76 | ALDH1A1 (0.36) | KISS1RALDH1A1RNPEPTDP1SLC7A5 | |
| SCHEMBL19230444 | 0.76 | ALDH1A1 (0.36) | KISS1RALDH1A1RNPEPTDP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016517-A1 | NAPHTHALENESULFONYL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 复旦大学 | 2023-02-16 | — | — | WO | disclosed |