Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 9/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324146 | 0.83 | GRIN2B (0.47) | KDM1ASLC6A4MAOA | |
| SCHEMBL29081462 | 0.83 | GRIN2B (0.47) | KDM1ASLC6A4MAOA | |
| SCHEMBL30141966 | 0.82 | KDM1A (0.45) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL16403103 | 0.82 | KDM1A (0.45) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL25053269 | 0.81 | GRIN2B (0.42) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| Hydrochloric Acid SCHEMBL29115976 | 0.80 | GRIN2B (0.41) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| Hydrochloric Acid SCHEMBL30661802 | 0.80 | GRIN2B (0.41) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL8085859 | 0.76 | SMN1; SMN2 (0.49) | KDM1AMAOBCISD1SLC6A2HTR1B | |
| SCHEMBL24363923 | 0.76 | CHRNA7 (0.46) | KDM1AMAOBCHRNA7MAOA | |
| SCHEMBL3438950 | 0.76 | CHRNA7 (0.46) | KDM1AMAOBCHRNA7MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |