Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529071 | 0.93 | FAAH (0.57) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7151887 | 0.93 | FAAH (0.57) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7098518 | 0.93 | FAAH (0.57) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7151886 | 0.93 | FAAH (0.57) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL31529223 | 0.93 | FAAH (0.57) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL31421853 | 0.90 | FAAH (0.47) | FAAHMEN1MAPK1KMT2ABIRC2 | |
| SCHEMBL26231755 | 0.89 | PLA2G10 (0.38) | FAAHMEN1MAPK1KMT2ABIRC2 | |
| SCHEMBL25052849 | 0.89 | PLA2G10 (0.38) | FAAHMEN1MAPK1KMT2ABIRC2 | |
| SCHEMBL17616958 | 0.87 | RECQL (0.39) | KMT2ABIRC2CAPN1 | |
| SCHEMBL17570956 | 0.87 | RECQL (0.39) | KMT2ABIRC2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018960-A1 | IMPROVED METHODS FOR PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2023-02-16 | — | — | WO | disclosed |