Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529071 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL31529223 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL7151886 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL7151887 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL31421853 | 0.94 | FAAH (0.47) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL25052856 | 0.93 | FAAH (0.49) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL28303046 | 0.92 | FAAH (0.60) | FAAHMEN1KMT2AASAH2SMN1; SMN2 | |
| SCHEMBL28303045 | 0.92 | FAAH (0.60) | FAAHMEN1KMT2AASAH2SMN1; SMN2 | |
| SCHEMBL21418111 | 0.88 | PSMB5 (0.51) | FAAHMEN1KMT2AMAPK1ASAH2 | |
| SCHEMBL21434187 | 0.83 | FAAH (0.65) | FAAHMEN1KMT2AMAPK1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |