Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077230 | 0.80 | RIPK1 (0.49) | RIPK1GRM5KMT2ADRD4MEN1 | |
| SCHEMBL4297768 | 0.76 | MAOB (0.43) | RIPK1MAOBMAOACARM1PRMT6 | |
| SCHEMBL29892012 | 0.74 | RIPK1 (0.52) | RIPK1TACR1 | |
| SCHEMBL29116012 | 0.74 | RIPK1 (0.52) | RIPK1TACR1 | |
| SCHEMBL4096504 | 0.73 | MAOB (0.38) | RIPK1MAOBMAOACARM1PRMT6 | |
| SCHEMBL16474198 | 0.73 | KDM4E (0.39) | RIPK1KDM4EMAOBMAOACARM1 | |
| SCHEMBL25053379 | 0.71 | KDM4E (0.43) | RIPK1KDM4EMAOBMAOACARM1 | |
| SCHEMBL18783100 | 0.69 | RIPK1 (0.54) | RIPK1MAOBMAOA | |
| SCHEMBL25053573 | 0.69 | KDM4E (0.41) | RIPK1KDM4EMAOBMAOACARM1 | |
| SCHEMBL4294410 | 0.68 | RIPK1 (0.50) | RIPK1MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |