Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25056522 | 0.82 | NPC1 (0.40) | ALDH1A1MAPTGAAHPGDSKIT | |
| SCHEMBL15507787 | 0.77 | TTK (0.51) | CYP11B2ALDH1A1MAPTGAAHPGDS | |
| SCHEMBL30132210 | 0.77 | TTK (0.51) | CYP11B2ALDH1A1MAPTGAAHPGDS | |
| SCHEMBL16968079 | 0.77 | ALDH1A1 (0.49) | CYP11B2ALDH1A1MAPTGAAHPGDS | |
| SCHEMBL15507905 | 0.70 | ALDH1A1 (0.54) | CYP11B2ALDH1A1MAPTGAAHPGDS | |
| SCHEMBL27950305 | 0.70 | PIK3CD (0.45) | ALDH1A1MAPTKITCYP3A4PRMT5 | |
| SCHEMBL21737683 | 0.70 | CYP11B2 (0.40) | CYP11B2ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL31607677 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTGAACYP3A4MEN1 | |
| SCHEMBL6863931 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTGAACYP3A4MEN1 | |
| SCHEMBL30839809 | 0.70 | ALDH1A1 (0.67) | ALDH1A1MAPTGAACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137484-A1 | TRICYCLIC COMPOUNDS AS EGFR INHIBITORS | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-22 | — | — | EP | disclosed |