Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 4/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620552 | 0.84 | HPGD (0.56) | HSD17B10HPGDHTTMEN1LMNA | |
| SCHEMBL1781420 | 0.78 | ADORA2B (0.43) | HSD17B10HPGDHTTGSK3BPIK3CA | |
| SCHEMBL10006721 | 0.76 | HPGD (0.38) | HSD17B10HPGDHTTKMT2ABCL6 | |
| SCHEMBL30328166 | 0.76 | HPGD (0.38) | HSD17B10HPGDHTTBCL6GRIN1 | |
| SCHEMBL4184831 | 0.74 | HSD17B10 (0.39) | HSD17B10HPGDHTTGSK3BBCL6 | |
| SCHEMBL29651071 | 0.74 | GSK3B (0.64) | HSD17B10HPGDHTTMEN1KMT2A | |
| SCHEMBL23620537 | 0.74 | PRKDC (0.49) | PRKDCPIK3CA | |
| SCHEMBL29502052 | 0.74 | PRKDC (0.49) | PRKDCPIK3CA | |
| SCHEMBL23452636 | 0.73 | PRKDC (0.62) | PRKDCPIK3CA | |
| SCHEMBL20299401 | 0.73 | PRKDC (0.62) | PRKDCPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137491-A1 | IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2023-02-22 | — | — | EP | disclosed |