Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 16/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30328953 | 0.85 | ADORA2A (0.32) | GRIN1GRIN2B | |
| SCHEMBL25164044 | 0.83 | USP1 (0.39) | USP1 | |
| SCHEMBL25164095 | 0.79 | POLB (0.36) | USP1GRIN1GRIN2B | |
| SCHEMBL4184836 | 0.78 | PDE4A (0.43) | HPGDHTTHSD17B10 | |
| SCHEMBL23620552 | 0.77 | HPGD (0.56) | HPGDHTTHSD17B10 | |
| SCHEMBL1693503 | 0.77 | HPGD (0.54) | HPGDHTTHSD17B10USP1 | |
| SCHEMBL25057366 | 0.76 | HSD17B10 (0.44) | HPGDHTTHSD17B10BCL6GRIN1 | |
| SCHEMBL30031420 | 0.74 | PIK3CA (0.46) | HTTHSD17B10USP1 | |
| SCHEMBL23625347 | 0.74 | USP1 (0.42) | HPGDHTTHSD17B10USP1GRIN1 | |
| SCHEMBL24787066 | 0.74 | USP1 (0.38) | HPGDHTTHSD17B10USP1BCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |