Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058097 | 0.99 | PDGFRB (0.36) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL19890923 | 0.73 | PDGFRB (0.43) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL21711086 | 0.71 | MAPT (0.33) | — | |
| SCHEMBL22176507 | 0.70 | FFAR4 (0.41) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL25058001 | 0.66 | LRRK2 (0.41) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL22435586 | 0.66 | PDE4A (0.40) | — | |
| SCHEMBL18079652 | 0.64 | FFAR4 (0.38) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL18079659 | 0.64 | FFAR4 (0.38) | PDGFRBPDGFRALOXLOXL2FFAR4 | |
| SCHEMBL25058151 | 0.62 | HSP90AA1 (0.39) | CRHR1 | |
| SCHEMBL19862428 | 0.62 | CDK4 (0.41) | PDGFRBPDGFRAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |