SCHEMBL2505909

SCHEMBL2505909

COC1O[C@H](C)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
M6PR P20645 2/20 0.44
MGAM O43451 4/20 0.40
SI P14410 4/20 0.40
G6PD P11413 2/20 0.38
FUCA1 P04066 1/20 0.38
AMY1A P0DUB6 1/20 0.36
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
SYNJ2 O15056 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12070982 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15215703 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15121661 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15273797 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL2233716 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL24605082 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL1832193 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15273793 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL13509342 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL767128 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274341-B1 INHIBITORS OF PSEUDOMONAS AERUGINOSA LECB HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) 2022-11-02 EP disclosed
US-11389466-B2 Multivalent fucose derivatives for use as a drug UNIVERSITE DE NANTES (FR) 2022-07-19 US disclosed
EP-3582789-B1 MULTIVALENT FUCOSE DERIVATIVES FOR USE AS A DRUG UNIV NANTES (FR) 2022-06-22 EP disclosed
CN-107531686-B Inhibitors of pseudomonas aeruginosa LecB 亥姆霍兹感染研究中心有限责任公司 2021-07-09 CN disclosed
CN-108495656-B Antibacterial composition containing deoxyhexose alkyl monoacetal or monoether 特雷奥斯淀粉及甜味剂比利时公司 2021-02-02 CN disclosed
US-20200281956-A1 ANTIBACTERIAL COMPOSITION CONTAINING A DEOXYHEXOSE ALKYL MONOACETAL OR MONOETHER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-09-10 US disclosed
US-20200268782-A1 MULTIVALENT FUCOSE DERIVATIVES FOR USE AS A DRUG NANTES UNIVERSITE (FR) 2020-08-27 US disclosed
US-10407398-B2 Inhibitors of Pseudomonas aeruginosa LecB Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2019-09-10 US disclosed
EP-3389731-A1 ANTIBACTERIAL COMPOSITION CONTAINING A DEOXYHEXOSE ALKYL MONOACETAL OR MONOETHER Tereos Starch & Sweeteners Belgium (BE) 2018-10-24 EP disclosed
WO-2018149945-A1 MULTIVALENT FUCOSE DERIVATIVES FOR USE AS A DRUG UNIVERSITE DE NANTES (FR) 2018-08-23 WO disclosed
US-6468688-B2 CHARGING, DISCHARGING EFFICIENCY; VANADIUM ELECTROLYTE PINNACLE VRB LIMITED (AU) 2002-10-22 US disclosed
WO-2002055016-A2 INHIBITION OF NF-λB BY TRITERPENE COMPOSITIONS RES DEV FOUNDATION (US) 2002-07-18 WO disclosed
US-6358293-B1 Methods for rendering high concentrations of manganese safe for plant growth and formulations for same THE HAMPSHIRE CHEMICAL CORPORATION 2002-03-19 US disclosed
US-20010028977-A1 Charging, discharging efficiency; vanadium electrolyte JD HOLDING INC. (KY) 2001-10-11 US disclosed
WO-2001038262-A1 METHODS FOR RENDERING HIGH CONCENTRATIONS OF MANGANESE SAFE FOR PLANT GROWTH AND FORMULATIONS FOR SAME HAMPSHIRE CHEMICAL CORPORATION (US) 2001-05-31 WO disclosed
EP-1027309-A4 METHODS AND COMPOSITIONS FOR ENHANCING GROWTH OF LIVING ORGANISMS NONOMURA ARTHUR M (US) 2001-04-11 EP disclosed
EP-1027309-A1 METHODS AND COMPOSITIONS FOR ENHANCING GROWTH OF LIVING ORGANISMS NONOMURA, Arthur M. (US) 2000-08-16 EP disclosed
WO-1999012868-A1 METHODS AND COMPOSITIONS FOR ENHANCING GROWTH OF LIVING ORGANISMS NONOMURA ARTHUR M (US) 1999-03-18 WO disclosed
EP-0275431-B1 NOVEL ANTHRACYCLINE DERIVATIVES, A PROCESS FOR PREPARING SAME AND THEIR USE AS MEDICAMENTS MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1992-09-23 EP disclosed
EP-0275431-A1 Novel anthracycline derivatives, a process for preparing same and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1988-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11389466-B2 Multivalent fucose derivatives for use as a drug FUCA2, FUCA1, FUT6 M6PR 152/4885MGAM 82/4885SI 1165/4885
US-10407398-B2 Inhibitors of Pseudomonas aeruginosa LecB FUCA1, ALG1, FUCA2 M6PR 470/4885MGAM 185/4885SI 1826/4885
US-20200281956-A1 ANTIBACTERIAL COMPOSITION CONTAINING A DEOXYHEXOSE ALKYL MONOACETAL OR MONOETHER DPM1, GNE, DERA M6PR 270/4885MGAM 11/4885SI 378/4885
US-20200268782-A1 MULTIVALENT FUCOSE DERIVATIVES FOR USE AS A DRUG FUCA2, FUCA1, FUT6 M6PR 152/4885MGAM 82/4885SI 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.