Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104788 | 0.90 | MAPK14 (0.56) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25064145 | 0.87 | HDAC6 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24935698 | 0.86 | ACACB (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12090019 | 0.83 | EPHX1 (0.67) | HDAC6MAPK14EPHX1EPHX2LMNA | |
| SCHEMBL25442206 | 0.81 | NAMPT (0.53) | MAPK14EPHX1EPHX2LMNARAB9A | |
| SCHEMBL12089859 | 0.81 | SMYD3 (0.53) | MAPK14EPHX1EPHX2LMNARAB9A | |
| SCHEMBL25063726 | 0.81 | CNR2 (0.46) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12090016 | 0.80 | NAMPT (0.58) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12017927 | 0.76 | LMNA (0.58) | LMNARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL21078070 | 0.74 | CHEK2 (0.50) | HDAC6EPHX1EPHX2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054270-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054270-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | AR, SHBG, NR5A1 | HDAC6 2550/4885HDAC3 3550/4885HDAC4 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.