Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 19/20 | 0.69 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25065629 | 1.00 | TLR4 (0.69) | TLR4LY96 | |
| SCHEMBL22922967 | 0.92 | TLR4 (0.76) | TLR4LY96 | |
| SCHEMBL29224847 | 0.92 | TLR4 (0.76) | TLR4LY96 | |
| SCHEMBL21256938 | 0.92 | TLR4 (0.76) | TLR4LY96 | |
| SCHEMBL7125999 | 0.88 | TLR4 (0.88) | TLR4LY96 | |
| SCHEMBL22922962 | 0.85 | TLR4 (0.86) | TLR4LY96 | |
| SCHEMBL22922963 | 0.85 | TLR4 (0.86) | TLR4LY96 | |
| SCHEMBL3938421 | 0.85 | TLR4 (0.83) | TLR4LY96 | |
| SCHEMBL25065631 | 0.84 | TLR4 (0.84) | TLR4LY96 | |
| SCHEMBL23252094 | 0.81 | TLR4 (1.00) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055805-A1 | TOLL-LIKE RECEPTOR LIGANDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055805-A1 | TOLL-LIKE RECEPTOR LIGANDS | TLR1, TLR4, TLR6 | TLR4 2/4885LY96 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.