Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2509504 | 0.95 | ALDH1A1 (0.31) | MCL1 | |
| SCHEMBL2503349 | 0.86 | — | — | |
| SCHEMBL3250338 | 0.80 | — | — | |
| SCHEMBL2511932 | 0.75 | RECQL (0.31) | — | |
| SCHEMBL2483956 | 0.73 | PLA2G7 (0.31) | MCL1 | |
| SCHEMBL2510860 | 0.70 | — | — | |
| SCHEMBL416328 | 0.69 | PPARD (0.37) | — | |
| SCHEMBL415213 | 0.68 | KMT2A (0.43) | — | |
| SCHEMBL418373 | 0.67 | NPC1 (0.41) | — | |
| SCHEMBL416574 | 0.67 | TNF (0.39) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |