Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 6/20 | 0.42 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933968 | 0.84 | SYK (0.51) | CTSCSYKCDK1 | |
| SCHEMBL1935796 | 0.81 | CTSC (0.48) | JAK2LRRK2CCNKCCND3CDK9 | |
| SCHEMBL1935999 | 0.79 | JAK2 (0.44) | JAK2LRRK2CDK9CTSCSYK | |
| SCHEMBL13252152 | 0.76 | BRAF (0.49) | MEN1KMT2ASYKCDK1 | |
| SCHEMBL993953 | 0.75 | JAK2 (0.66) | JAK2LRRK2MEN1KMT2ACTSC | |
| SCHEMBL24842798 | 0.74 | CTSC (0.63) | JAK2LRRK2CCNKCCND3CDK9 | |
| SCHEMBL29816818 | 0.74 | CTSC (0.63) | JAK2LRRK2CCNKCCND3CDK9 | |
| SCHEMBL1936649 | 0.74 | MET (0.40) | JAK2LRRK2CCND3CTSCSYK | |
| SCHEMBL1936655 | 0.74 | SYK (0.44) | JAK2LRRK2CTSCSYKJAK1 | |
| SCHEMBL1938235 | 0.73 | SYK (0.50) | CCNKCCND3CDK9CDK6CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| CN-102203070-A | Alkoxy-and alkylthio-substituted anilinopyrimidines | BAYER CROPSCIENCE AG | 2011-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | HAX1, AGPS, PYM1 | JAK2 1279/4885LRRK2 1592/4885CCNK 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.