Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041564 | 0.83 | POLB (0.69) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL29823822 | 0.83 | POLB (0.69) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL10472032 | 0.82 | POLB (0.55) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL541725 | 0.81 | POLB (0.54) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL6200992 | 0.79 | KMT2A (0.51) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL27604268 | 0.79 | POLB (0.53) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL10857506 | 0.78 | HPGD (0.44) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL28433719 | 0.78 | POLB (0.58) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL8500940 | 0.78 | KMT2A (0.52) | POLBHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL29548224 | 0.78 | DRD3 (0.63) | POLBHSD17B10KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | DCX, NES, MCL1 | POLB 2058/4885HSD17B10 783/4885KDM4E 3461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.