Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823822 | 1.00 | POLB (0.69) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7128071 | 0.90 | KMT2A (0.76) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28433719 | 0.90 | POLB (0.58) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11398510 | 0.90 | KMT2A (0.60) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11067835 | 0.90 | KMT2A (0.60) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10472032 | 0.89 | POLB (0.55) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28331881 | 0.89 | POLB (0.56) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL17775892 | 0.89 | KMT2A (0.62) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL541725 | 0.88 | POLB (0.54) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11401440 | 0.88 | KMT2A (0.84) | POLBALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385856-A | Method for synthesizing norfloxacin intermediate by one-pot method | 常州大学 | 2022-11-25 | — | — | CN | claimed |
| CN-114853671-A | Preparation method of norfloxacin impurity | 深圳振强生物技术有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-104774178-A | Preparation method of ethyl 7-chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate | UNIV ZHEJIANG SCIENCES | 2015-07-15 | — | — | CN | claimed |
| JP-62294689-A | — | — | None | — | — | JP | disclosed |
| CN-109225114-B | Self-circulation tubular reaction device with efficient mixer and reaction method adopting self-circulation tubular reaction device | 葛沁怡 | 2024-07-12 | — | — | CN | disclosed |
| CN-115385856-A | Method for synthesizing norfloxacin intermediate by one-pot method | 常州大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-114853671-A | Preparation method of norfloxacin impurity | 深圳振强生物技术有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-107406390-B | Modulators of monocarboxylic acid transporters and uses thereof | 奈吉治疗公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3221295-B1 | MONOCARBOXYLATE TRANSPORT MODULATORS AND USES THEREOF | NIROGY THERAPEUTICS INC (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-3221295-B1 | MONOCARBOXYLATE TRANSPORT MODULATORS AND USES THEREOF | NIROGY THERAPEUTICS INC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-10766863-B2 | Monocarboxylate transport modulators and uses thereof | NIROGYONE THERAPEUTICS, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| EP-0280241-A2 | Platen roller | CANON KABUSHIKI KAISHA (JP) | 1988-08-31 | — | — | EP | disclosed |
| EP-0250535-A1 | NORFLOXACIN INTERMEDIATE. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-01-07 | — | — | EP | disclosed |
| EP-0249620-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-23 | — | — | EP | disclosed |
| JP-S62294689-A | QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1987-12-22 | — | — | JP | disclosed |
| WO-1987003595-A1 | NORFLOXACIN INTERMEDIATE | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |
| WO-1987003587-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |
| CN-86103954-A | Preparation has the method for quinolone carboxylic acid ester's class of anti-microbial activity | — | 1987-01-28 | — | — | CN | disclosed |
| US-4472579-A | REACTING A PIPERAZINE WITH A CHLORO QUINOLINECARBOXYLIC ACID ESTER, HYDROLYSIS | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4292317-A | BACTERICIDES FOR GRAM NEGATIVE AND -POSITIVE BACTERIA; ANIMAL GROWTH REGULATORS | LABORATORIE ROGER BELLON (FR) | 1981-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766863-B2 | Monocarboxylate transport modulators and uses thereof | SLC16A1, SLC16A3, SLC16A7 | POLB 4243/4885ALDH1A1 521/4885HPGD 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.