Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697359 | 0.85 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19GUCY1A1GUCY1B1 | |
| SCHEMBL25070271 | 0.83 | GPR119 (0.33) | KDM4ERAB9AHPGDALDH1A1HIF1A | |
| SCHEMBL21246137 | 0.76 | POLB (0.40) | KDM4ERAB9AHPGDALDH1A1HIF1A | |
| SCHEMBL25070273 | 0.73 | BRD4 (0.31) | IRAK4 | |
| SCHEMBL25070274 | 0.72 | TLR8 (0.32) | — | |
| SCHEMBL25069986 | 0.72 | SMN1; SMN2 (0.42) | KDM4ERAB9AHPGDALDH1A1NPC1 | |
| SCHEMBL21285337 | 0.70 | KDM4E (0.46) | KDM4ERAB9AHPGDALDH1A1NPC1 | |
| SCHEMBL20689532 | 0.70 | KDM4E (0.41) | KDM4ERAB9AHPGDALDH1A1NPC1 | |
| SCHEMBL20688924 | 0.68 | KDM4E (0.44) | KDM4ERAB9AHPGDALDH1A1NPC1 | |
| SCHEMBL26256567 | 0.68 | KDM4E (0.47) | KDM4ERAB9AHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056447-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056447-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | CYP1A2 3935/4885CYP3A4 4404/4885CYP2C19 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.