Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16885012 | 0.92 | HPGD (0.47) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL21134083 | 0.90 | HPGD (0.46) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL21914798 | 0.81 | CYP3A4 (0.33) | HPGDMAPTALDH1A1POLBCYP2C9 | |
| SCHEMBL25070531 | 0.80 | NR1H4 (0.32) | NR1H4TARBP2 | |
| SCHEMBL25070562 | 0.79 | CYP2D6 (0.37) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20806064 | 0.78 | NR1H4 (0.42) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL15871088 | 0.73 | XDH (0.44) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL22298999 | 0.73 | NR1H4 (0.38) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL14799791 | 0.71 | KDM4E (0.44) | HPGDMAPTKDM4EALDH1A1POLB | |
| SCHEMBL21815405 | 0.71 | NISCH (0.35) | MAPTKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |