SCHEMBL14799791

SCHEMBL14799791

CC(C)COc1ccc(-c2ccc(-c3ccc(OCC(C)C)cc3)c3nn(CC(C)C)nc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.44
▸ ALDH1A1 P00352 4/20 0.44
▸ MAPT P10636 4/20 0.44
▸ HPGD P15428 3/20 0.44
▸ POLB P06746 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ NPC1 O15118 3/20 0.43
▸ RAB9A P51151 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TSHR P16473 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ AAK1 Q2M2I8 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ MCL1 Q07820 1/20 0.41
▸ NR1H4 Q96RI1 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16402077 0.89 MEN1 (0.39) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL28527296 0.86 MEN1 (0.42) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL16401994 0.84 MEN1 (0.42) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL14799787 0.83 KMT2A (0.39) MAPTPOLBKMT2AMDM2MCL1
SCHEMBL17281139 0.81 XDH (0.42) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL14799643 0.81 SMPD1 (0.51) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL15871101 0.80 SMPD1 (0.41) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL16885012 0.78 HPGD (0.47) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL15871124 0.78 MAPT (0.39) KDM4EALDH1A1MAPTHPGDPOLB
SCHEMBL14799716 0.78 NPC1 (0.43) KDM4EALDH1A1MAPTHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190284471-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES CHOSHU INDUSTRY CO., LTD. (JP) 2019-09-19 — — US disclosed
US-20190284471-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES CHOSHU INDUSTRY CO., LTD. (JP) 2019-09-19 — — US disclosed
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics NITTO DENKO CORPORATION (JP) 2018-05-17 — — US disclosed
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics NITTO DENKO CORPORATION (JP) 2018-05-17 — — US disclosed
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics NITTO DENKO CORPORATION (JP) 2018-05-17 — — US disclosed
EP-2978820-B1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORP (JP) 2018-03-21 — — EP disclosed
US-20160276514-A1 SOLAR ENERGY COLLECTION SYSTEMS UTILIZING HOLOGRAPHIC OPTICAL ELEMENTS USEFUL FOR BUILDING INTEGRATED PHOTOVOLTAICS NITTO DENKO CORPORATION (JP) 2016-09-22 — — US disclosed
US-20160276514-A1 SOLAR ENERGY COLLECTION SYSTEMS UTILIZING HOLOGRAPHIC OPTICAL ELEMENTS USEFUL FOR BUILDING INTEGRATED PHOTOVOLTAICS NITTO DENKO CORPORATION (JP) 2016-09-22 — — US disclosed
US-20160276514-A1 SOLAR ENERGY COLLECTION SYSTEMS UTILIZING HOLOGRAPHIC OPTICAL ELEMENTS USEFUL FOR BUILDING INTEGRATED PHOTOVOLTAICS NITTO DENKO CORPORATION (JP) 2016-09-22 — — US disclosed
EP-3065182-A1 WAVELENGTH-CONVERSION ENCAPSULANT COMPOSITION, WAVELENGTH-CONVERTED ENCAPSULANT LAYER, AND SOLAR CELL MODULE USING SAME Nitto Denko Corporation (JP) 2016-09-07 — — EP disclosed
US-20160254405-A1 WAVELENGTH-CONVERSION ENCAPSULANT COMPOSITION, WAVELENGTH-CONVERTED ENCAPSULANT LAYER, AND SOLAR CELL MODULE USING SAME CHOSHU INDUSTRY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138346-A1 Solar Energy Collection Systems Utilizing Holographic Optical Elements Useful for Building Integrated Photovoltaics CRY1, CRY2, AXIN2 KDM4E 4150/4885ALDH1A1 3311/4885MAPT 361/4885
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KDM4E 983/4885ALDH1A1 1484/4885MAPT 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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